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@toolbelt and to michaelcharles, thanks for that discussion. I'm starting on Orgovyx next week, then 28 days of IMRT the following week. After doing Antera AI testing I thought I was in the clear for no ADT. I had multiple consultations where I always asked the docs if they trusted the AI part of AnterraAI, and all said sure, why not. The RT Team I decided to go with said they didn't trust just AnteraAI alone and wanted to add Decipher testing just to make sure. It was a shock to me that Decipher pointed out I have a more aggressive form of Pc than my staging indicted and thus the last minute added need for ADT. Quick research, and the shared experiences of this discussion board, have moved me to choose Ogovyx over Lupron injections. For all the same reasons that you have stated. Reportedly fewer or at least less intense side effects, knowing that I can stop that treatment if it is overwhelming, and at least the illusion that I have some daily control. In reality, I will do just as the doctor orders, the alternative is what I'm trying to avoid at all costs. Best wishes for success to you two and all the members of the club on this discussion board. Invaluable.
Replies to "@toolbelt and to michaelcharles, thanks for that discussion. I'm starting on Orgovyx next week, then 28..."
@jesse65 I too had both the Decipher and Artera-ai test. In my case they essentially agreed with a 0.81 Decipher and a true on Artera-ai. But the main point of doing both is for the situation you are in where one test might override the other and you would go with the conservative result. I was only a 3+4 so ADT was in question initially, but I ended up with one year of Lupron. Sure wish I had done Orgovyx so my testosterone would have come back faster. But for a 4+3 case like yours, only a false on Artera-ai and a low Decipher score together would have justified no ADT. See my bio for more details.
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@jesse65 To clarify, I'm 65, PSA 5, Gleason 4+3=7. Diagnosed in October this year, negative PSMA PET. Met with some of the top institutions and considered surgery, proton, and SBRT. Almost went Proton, but talked out of it by two proton therapy providers.