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Transitioning from Plaquenil (hydroxychloroquine) to Methotrexate
Transitioning from Plaquenil (hydroxychloroquine) to Methotrexate
Posted by nettsie @nettsie, 2 days ago
My doctor has recommended switching from hydroxychloroquine to Methotrexate. As explained I would continue taking hydroxychloroquine for about a month while starting with a low dose of Methotrexate.
I would appreciate hearing about anyone's experience with this.
Thank you.
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Methotrexate (MTX) can negatively affect bones, leading to osteoporosis, bone pain, and fractures, especially at the high doses used for cancer, but even lower doses for arthritis can sometimes cause issues (called MTX osteopathy). I took methotrexate for my rheumatoid arthritis when I was young and now I have severe osteoporosis.
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4 Reactions@maymore Same with my 84 year-old husband, who has severe kyphosis and now has his 6th spinal compression fracture. Doctor has only blamed it on Rheumatoid Arthritis.
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2 ReactionsHydroxy to Methotrexate… You didn’t mention your Diagnosis?
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1 ReactionPolyarthritis and Osteoporosis
Thank you for asking.
Thank you for sharing. I too was taking Hyroxy but for LUPUS which I ended up testing negative. I'm still pursuing a Diagnosis. Blessings.
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1 Reaction@maymore
What do you take now?
I don't take anything for the rheumatoid arthritis because it is gone since I went on an anti-inflammatory, plant-based diet, but for the osteoporosis I take Raloxifene.
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1 Reaction@maymore Why does he want to take you off a drug that does not cause bone loss to a drug that does?
@dvargo. Raloxifen does not cause bone loss. It’s supposed to build bones.