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DiscussionDeveloped bronchitis like cough, nasal congestion: can't stabilize
MAC & Bronchiectasis | Last Active: 1 day ago | Replies (32)Comment receiving replies
Replies to "@tcd518 Thank you for clarifying, I have BE When I get any illness it turns into..."
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@taracronwall
Brinsupri is not for "killing bacteria" it is for the continuous cycle of inflammation that is a big problem with bronchiectasis.
The bronchiectasis inflammatory cycle, often called a "vicious cycle" or "vortex," is a self-perpetuating loop where airway damage leads to mucus buildup, trapping bacteria, which triggers intense inflammation (especially neutrophilic), releasing enzymes that further damage airways, causing thickening and dilation, hindering mucus clearance, and perpetuating infection and inflammation. This cycle involves impaired mucociliary clearance, chronic infection, sustained inflammation (neutrophils, macrophages, lymphocytes), and structural airway damage, creating a progressive, damaging feedback loop that worsens lung function.