@jijianhua I’m not a doctor so don’t listen to me. His measurements sound low for an 11 yo. How are his growth hormone levels? It could be a pituitary macro adenoma. With a good neurosurgeon this can be fixed with hopefully no hormone therapy needed. I didn’t develop diabetes incipidus until after my surgery so that isn’t always a symptom to go by. Best of luck. I hope everything works out well.