I am a Board-Certified Healthcare Professional. I started BHRT recently, 17 years Post-Menopause. My medical history shows no Cardiovascular or Stroke occurrence. My Ob-Gyn cautioned against starting hormone therapy stating it would not help my Osteoporosis condition. Since there has been a black box removal of using BHRT , many healthcare professionals discuss the benefits to the brain, heart, mood, bone, etc. I am on a low dose of Estradiol, Micronized Progesterone, Testosterone. At this time it has benefited me.