Updated info after discontinuing Prolia after 4 injections. My last Prolia injection was October of 2024. I had good cholesterol readings prior and during my time on prolia my cholesterol skyrocketed to the point of advertising me to take atorvastatin, which I refused. I just received my wellness yearly lab work last week and my cholesterol readings were optimal. All in good range. As a side note, I did stop prolia and chose no other pharma meds and only added collagen peptide to what I was already taking which is plant based calcium and Vit D. I will be looking for a Rems test towards the end of the year vs. the DEXA because I have osteoarthritis which can show as a better bmd. Be sure to get your cholesterol checked if on prolia.