← Return to Stopped Prolia due to upcoming dental surgery

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ariespumpkin, when was your last Prolia injection?
You may know about Prolia rebound, but in case you don't you might want to know that it is a hazardous to even be late for the six month injection. Prolia stops the development of cells that breakdown bone. It stops them in the very last stage of development. It doesn't cause these cells to die, but collects them in what they call reservoirs of cells that sometimes combine to become super bone eating cells. But when you stop Prolia all these cells rapidly finish developing and are released. The effect on your bones is devastation. Patients experience multiple fractures called cascade fractures.
Prolia is the only medication that will leave you worse off than if you'd never taken it unless you follow it with a strong antiresorptive. Reclast is the strongest and even Reclast is sometimes not adequate to ward off those cells. The bisphosphonates including reclast which also carries a risk for osteonecrosis.
I've come to the thinking that the best solution in this situation is to add Forteo to Prolia. Together they offer more bone acquisition than the drugs alone. And Forteo is prescribed for the difficult to remedy bone osteonecrosis.
Your oral surgeon may be able to order Forteo for you, though I've spoken to several lately who are unaware of the medication.
Two important consideration are how long you have been on Prolia and when was your last injection.
I'd ask the oral surgeon about Forteo. They may understand your situation. But also try to get into an endocrinology office and general practitioners office whichever is soonest.

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Replies to "ariespumpkin, when was your last Prolia injection? You may know about Prolia rebound, but in case..."

@gently I appreciate this information. My last injection was in June 2025; I was scheduled for my next injection on the 5th of January 2026, but cancelled the appointment due to the upcoming surgery. I will contact my dentist regarding my issue ASAP. Appreciate your response.