← Return to Xtreme PSA bounces after radiation cancer or inflammation?

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@neilmartin This is where we have to be careful with one specialist’s opinion (even at Centers of Excellence) unless they can show data to back it up. (I always asked my Uro, RO, and MO to “show me” or “where can I find that?” so that I could look it up for myself. Not that I didn’t believe them, but if something is going to happen to me - possibly something bad - I want to have buy-in first.)

What one doctor might call “the spike of the century,” this doctor at a PCRI conference a few years ago said that “…the typical bounce is in the 1, to 2, 3 range.” Then he goes on to say that “I have had patients at 10; I had one guy at 16 and didn’t treat them. They didn’t want to go with treatment and waited, and their PSA went away.”

See that PCRI Conference interview at: https://youtu.be/ogDhQv-1Axo (starting at about the 6:00 minute mark). The full interview is less than 8 minutes so, you might want to watch the whole thing just to have context.

I bookmarked that interview a couple of years ago because when I heard him say PSA bounces to “10….16” that seemed so far beyond everything that I had heard/read elsewhere.
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My personal view is that doctors aren’t gods - they’re just people like you and me. They’re working in an occupation for which they have an aptitude and great passion for (and I respect them for that); but, they’re not perfect; they’re human, with human frailties; they sometimes make errors. (No different than you and I who were very good in our individual careers and the teams we worked with, but we weren’t perfect.)

So, they’re not always right; no one doctor knows everything; they only know as much as they’ve learned and experienced. Whatever they tell me, I accept it with some cautious and informed skepticism (and optimism).

(Ok..,,off my soapbox.)

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Replies to "@neilmartin This is where we have to be careful with one specialist’s opinion (even at Centers..."

@brianjarvis and heavyphil,

Thank you for your insights and efforts on this topic. You make this group very valuable. Hopefully as I transition through this I can add to body of knowledge for the rest of the group. I will post again here as things unfold.

@brianjarvis
Saw the video and it definitely is interesting. I wonder if, when they had that big jump, the PSMA pet was available. It definitely appeared to be unusual since he only had a couple of cases that had huge jumps.

In this case, we weren’t discussing treatment, however we were discussing getting a scan. You run into the other side of this issue where a metastasis may have actually come up, resulting in the significant PSA rise and looking for it was beneficial. That has definitely occurred many times with people I have heard from an online meetings. Prostate cancer, cancer, present, challenging Issues.