Connect
← Return to A cautionary tale for those on ADT: Lupron and Osteoporosis
Discussion
A cautionary tale for those on ADT: Lupron and Osteoporosis
Prostate Cancer | Last Active: Mar 29 9:27pm | Replies (30)Comment receiving replies
@jeffmarc
Yeah Jeff, this hits on the fine line between the presence of Lupron vs it's effects.
Chart attached shows 3-month interval injections but suppression of T is relatively constant due to the "steady state release" of Lupron in the bloodstream based on the concentration when it's administered. (Details here. Item 12.3 :
https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020517s036_019732s041lbl.pdf)
Lupron may be largely out of one's system but its effects, particularly to testosterone suppression as in mine and other's cases, continue. Possibly for much longer. My GU/oncologist also says this persistence of side effects increases with age. I was 76 when Lupron was started, 78 when concluded; I may be dealing with this for a while longer.
Thanks for your comments.
Replies to "@jeffmarc Yeah Jeff, this hits on the fine line between the presence of Lupron vs it's..."
Connect
@grandpun
Not sure you’ve read it, but I was on Lupron For six years and switched to Orgovyx For nine months when I stopped taking it. In seven months by testosterone went from undetectable to 50. I was 77 at the time. My testosterone was going up 25% a month.
My oncologist didn’t want me to stay off of ADT so I had to go back on Orgovyx. It wasn’t real fast, but after all those years, it was coming back pretty steadily.
The problem is everybody’s different with this recovery of testosterone. I’ve run into people that never had it come back And some of the online meetings I’ve attended. They are not happy and in most cases their doctors don’t want to give them testosterone injections.