← Return to Xtreme PSA bounces after radiation cancer or inflammation?

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Profile picture for neilmartin @neilmartin

@brianjarvis cancer was contained, low dechiper, no cribriform. Was on AS with three biopsies over 3 years. 3+4 , less than 5% 4 in 2 cores. The rate of change both up and down is more than I have seen. I can accept I am not cured but the rate of change seems unusual.

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Replies to "@brianjarvis cancer was contained, low dechiper, no cribriform. Was on AS with three biopsies over 3..."

@neilmartin Similar to mine. During the nearly 9 years that I was on active surveillance (with a 3+3), my PSA bounced around in an upward trajectory (see my attached PSA tracking chart).

Ultimately (when a 3+4 showed up), I decided on 28 sessions of proton beam radiation and SpaceOAR Hydrogel.

However, prior to starting treatments, a 2nd opinion upgraded the 7(3+4) to a 7(4+3).

Again, understanding that a Gleason score is a specialist’s educated, experienced opinion of what is seen in the biopsies tissues under a microscope - there was no way to know which one was “right.”

So, I made a commitment prior to the 2nd opinion:
> if the 2nd opinion came back a lower 6(3+3), I would still get treated to the current 7(3+4).
> if the 2nd opinion came back the same 7(3+4), I would get treated to the 7(3+4).
> if the 2nd opinion came back a higher 7(4+3), I would get treated to the higher 7(4+3).

As it turned out, the 2nd opinion came back a higher 7(4+3). So, we simply added 6 months (two 3-month injections) of Eligard to the treatment plan.

These days, PSA fluctuates between 0.3 - 0.5.