Thanks Terri for your reply. My name is Nasser. wife is back again on the 3 Big medicines (MAC) and tobramycin (Pseudomonas) for a month ago. I will ask her doctor to do a a susceptibility test. I will also discuss with him your maintenance doses; Cipro for 10 days bi-monthly, on the 'off' months, on doxycycline for 10 days. Further, on inhaled tobramycin till pseudo is knocked away. I am aware of Mayo clinic and wish treatment/advise are offered through a distance. Thank you again and a big "thank you" from my wife to you.