@readandlearn
Zytiga Is a drug that acts like ADT since it further suppresses testosterone like ADT, But it is an ARPI as I’m sure you’ve found out. I was on it for 2 1/2 years and it was never easy. I was only undetectable for one month in 2 1/2 years. My PSA kept going up and down.. When I stopped it, I had to have a metastasis in my spine zapped because it just didn’t work well enough. It did give me high blood pressure, lots of hot flashes and four afib events. Not an easy drug to live with for many people.

The problem with stopping the drugs is that the metastasis are not always killed when you’re on them. They shrink in size and stop growing completely, but they may be there to come back again. It could be proton radiation could enable you to have that one on your lymph gland zapped, If it comes back, need to speak to a radiation oncologist that does proton.

If they have you get back on ADT Try to get them to prescribe Nubeqa. Unlike Zytiga, it has very few side effects, Most people don’t notice any. Zytiga did not stop my PSA from going up and down, I’ve been undetectable for 26 months on Nubeqa.

Hopefully your PSA stays undetectable for a long time.