Severe postprandial abdominal pain, all tests clear. Need direction!

Welcome to Mayo Clinic Connect. Sorry to hear about your pain. Shaking and crying in pain with nausea sounds horrible.

It sounds as though you've been very diligent in going to be assessed for a variety of things by medical professionals.

Did the doctor or doctors who oversaw the testing you completed have any next steps for you? Theories?

@lisalucier Thank you for your response, but unfortunately, nothing significant was found; every doctor simply gave me the results without offering any solution. While it is true that most of the tests came back negative, the pain persists nonetheless, and no one can tell me why

@prelucku just keep fighting for yourself. Reach out to the major medical centers. Send your imaging around to them. I had to do that for my current issues (long story but ending up with restricted stomach outlet by an adhered bowel to a hernia mesh). What started as constant colorectal that yield no results due to my organs being "fine" but everything is scarring, adhesions, and pulling and tugging during normal operations.
Did your Drs do an MRE? Any contrast with the other tests? They may need to see what happens when you eat or breath in order to see how the organs all play together. You won't see that in normal imaging which is why I've had to force them to order it, and I just paid out of pocket for the sake of getting it done. Not sure what your insurance is like, but being on Medicaid in the US is decent-ish locally but it massively limits the speed and quality of care externally of your local jurisdiction which is where I'm at right now. Awaiting a corporation to approve me to be seen by Columbia Health in NYC. They've already accepted my case. They weren't too busy for me like Mayo is lol.
But keep advocating for yourself. If you're in pain you have to make them listen some how. Otherwise pain just is tossed aside like take some ibuprofen. They didn't care I had to do that daily just for bladder relief and couldn't pinpoint that as a symptom of what I already knew was happening.
Some of these medical professionals and Drs aren't in it for the patient. They're in it for their own egos, money, and stature. Find the right ones. I have dealt with residual issues since 2016 when I had my major diverticulitis issues and surgeries. Since then, it has been a part time job just to find the right Drs who will listen to me and advocate WITH and FOR me. Not just tell me I don't see anything, sorry. And lastly. If you're smart with it and use it correctly (and unfortunately use a more pro or paid version and NOT chatGPT), use AI as a companion. Do research but hone in on stuff or complex things with AI. I use Gemini Pro and it has been a huge help these last few months alone.
Good luck. And be careful simply saying "I have pain" in the Drs offices or studies. It's too easily dismissed. Explain it. In detail. The more you can detail it the more they can see it is serious and then not simply "under diagnose" you.

It sounds like mesenteric ischemia. You need to see a vascular doctor ASAP. It can be life threatening. My mother in law had this and my husband.
There are 3 main arteries that deliver blood to your intestines. My husband has stenosis in two of them.
It is a very rare condition and most GI docs and Emergency doctors always miss the diagnosis.
Pain after eating is the number one symptom.
There is a Facebook group for Mesenteric Ischemia UK based.
Please get your arteries checked. Main tests are an ultrasound to measure velocity of blood flow and a CT scan with contrast that looks specifically at the arteries.

Hello, @prelucku
Much of what you have written mirrors my wife’s experience. Many tests and imaging but nothing to fully account for the problem.

The pattern of symptoms is somewhat different but the point is that it was only when my wife had a CT scan in the midst of a protracted episode of nausea that a mid-level small bowel obstruction was found. The obstruction seems to be the source of much, if not all, of her misery. The timing was fortuitous. She was scheduled for a routine wellness examination but when she showed up with unrelenting nausea the doctor promptly sent her for that CT scan. Previous imaging absent the nausea attack failed to reveal it.

It sounds like mesenteric ischemia. You need to see a vascular doctor ASAP. It can be life threatening. My mother in law had this and my husband.
There are 3 main arteries that deliver blood to your intestines. My husband has stenosis in two of them.
It is a very rare condition and most GI docs and Emergency doctors always miss the diagnosis.
Pain after eating is the number one symptom.
There is a Facebook group for Mesenteric Ischemia UK based.
Please get your arteries checked. Main tests are an ultrasound to measure velocity of blood flow and a CT scan with contrast that looks specifically at the arteries.