@jeffmarc
The two drugs I was taking were Lupron (shot every 12 weeks) & Abiraterone (4 pills daily).

I stand corrected about ADT.

I was told by my oncologist that Lupron suppressed testosterone from the testes, & the Abiraterone was an ADT drug that suppressed testosterone from other androgen (adrenal) sources. Hence, the distinction. I now see from Google that I misunderstood part of that.

After I had been on ADT for 1.5 years, I decided to move to another state, from one 2-story house to another. I had help loading/unloading the four 8'x16' "Pods" with some furniture, but otherwise the beds, chairs, tables, & numerous boxes & computer equipment by myself. I have a slight frame & am not particularly muscular, having worked (like you) as a computer desk jockey for most of my life. I did not experience any fatigue over what I would normally have felt, but did lose some weight.

I did feel a slight increase in strength & balance when I dropped ADT the following year. If I had not known about the effects of ADT, I would have thought that the change was due to getting more exercise. I also gained 20 lbs (which I have since lost by diet).

If I go back onto ADT, I will probably ask about switching to Orgovyx. I had no post-injection symptoms, but like the idea of no brain fog. I don't know whether I had any brain fog due to Lupron, because forgetting stuff is not only part of getting older, but I had a head start. I often forget people's names that I don't regularly deal with, but then when I was on dates when I was 19, I forgot the name of my date sitting next to me in my car (this happened with two different dates). Fortunately, I was able to recall the names before I needed them. At least now I have an excuse, but don't need two.

About six months after surgery, when my PSA started to rise again, they did a PET scan & found a spot in a lymph gland 1cm from my lower aorta. The radiologist wanted to zap it, but my oncologist thought that was too close to the aorta, & offered ADT instead. I agreed.

If my PSA rises to 0.20 or above, my current oncologist wants to do another PET scan. If that happens, I will have to decide again about radiation or ADT. I have a bit more information now (from this forum), so it will be an interesting decision to make.