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Nubeqa (Darolutamide) versus Zytiga versus Estradiol Patches

Prostate Cancer | Last Active: 20 hours ago | Replies (15)
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Profile picture for jeff Marchi @jeffmarc

@sriddle1
It is approved for Metastatic castration-sensitive prostate cancer (mCSPC).

I don’t suppose you are castrate resistant yet. It is approved for that too.
https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-darolutamide-metastatic-castration-sensitive-prostate-cancer
I have found that when I want my oncologist to give me something different I ask for it. I don’t equivocate. I don’t ask if it’s OK I ask for it.. That’s because I know what the guidelines are and that it will be covered by insurance.

If you can’t get anywhere with this doctor, you might want to try getting a second opinion from a center of excellence.

Is your partner having a real problem with side effects of Zytiga? Like I did.

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Replies to "@sriddle1 It is approved for Metastatic castration-sensitive prostate cancer (mCSPC). I don’t suppose you are castrate..."
sriddle1 | @sriddle1 | 1 day ago

@jeffmarc thank you. I will ask her why he can’t have that. She made it sound like it wasn’t compatible with his disease and stage.

He has not yet started any type of treatment at this time except for his RP in October 2025. We just only met with her last week. She is MO at City of Hope where he is being treated. She has quite the resume too. I am just trying to figure out how to approach this. She will have to explain to us why he can’t be on Nubeqa as I can’t see a reason with the info I’m hearing and your response too.

Also, why is it that more men aren’t on Nubeqa? It seems are on Zytiga? Is that the case or just my assumption? I hear so many men having terrible side effects from the ADT meds and mostly read that it’s the Zytiga.

Thanks for your input and advice.

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