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Can a short term of taking Orgovyx cause leg pain and weight gain?
Prostate Cancer | Last Active: 23 hours ago | Replies (16)Comment receiving replies
@jeffmarc Thanks for your response. I don’t know what BRCA2 means. I’m 82, in 2009 stage 3 prostate cancer detected. Chemo & radiation for 42 weeks. Cancer returned 2023 & began a 2 year regimen of Orgovyx in February 2025. I just like to know that 1) is Orgovyx working and 2) that Orgovyx isn’t going to cripple me. I play golf 4 x per week but walking, squatting etc. is becoming difficult. I probably need knee replacement but at my age I’ll pass
Replies to "@jeffmarc Thanks for your response. I don’t know what BRCA2 means. I’m 82, in 2009 stage..."
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@tldrelaxen
BRCA2 Is a genetic problem. It greatly increase the chance of getting prostate cancer, Breast cancer, Pancreatic cancer, Skin, cancer, and a few other cancers.
You should talk to your doctor about putting you on a second drug. Staying on ADT like Orgovyx Alone can cause you to become castrate resistant. That greatly shortens the Life of many people. A drug like Nubeqa Has almost no side effects and would be a great addition for somebody your age. Taking it along with Orgovyx delays the onset of castrate resistance by many years.. I am 78 and on Orgovyx And Nubeqa. I know a lot of people and their 70s and 80s that are on only Nubeqa. It alone keeps the PSA way down because it prevents testosterone from working with prostate cancer calls. That allows people to give up ADT and stay with undetectable PSA. When your testosterone comes back, you feel a lot better.
After seven years on ADT, my oncologist and I figured my testosterone would never come back so I quit taking Orgovyx For seven months. My PSA stayed undetectable because I was on Nubeqa. Unfortunately, my testosterone started coming back pretty quickly And because of the BRCA2, my oncologist wanted me to go back on Orgovyx. I’ve had prostate cancer for 16 years and it has reoccurred four times. Unfortunately, I cannot stop the pills.
Just some things to think about and to discuss with your doctor.