@tsc I have GCA, diagnosed 8+ years ago. Actemra keeps me “out of trouble,” but does keep me with a form of anemia. I also have microscopic colitis and COPD. At 81 I’m thankful that I am still able to do many things, but I have had to learn to pace myself and adjust what I actually can do. That is often the greatest struggle, to admit where I am in life. Btw last year I broke my femur and after resisting for five years, am finishing up 12 months of evenity. I’ve recovered from breast cancer. I work hard to stay optimistic and know that my husband is extremely important in that regard. Positivity, even through pain, is some of the best medicine.