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@jeffmarc thanks for the information. I read somewhere in these comments that Orgovyx loses its effectiveness after 4 years. Some are taking it for a year then not until their PSA count increases. My big complaint with Orgovyx, I think it affects the tendons and bones around my knees to a point where I have trouble walking. I occasionally have chills also. I take my temperature and it is 1 degree below normal.

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Replies to "@jeffmarc thanks for the information. I read somewhere in these comments that Orgovyx loses its effectiveness..."

@tldrelaxen
I don’t think Orgovyx Is being used any different than other ADT drugs. Some people who have intermediate cases of prostate cancer may be on ADT for a year and decide that since their PSA has stayed undetectable for that amount of time, they will stop taking it and see what happens. This isn’t unusual, but it is done with all different ADT drugs.

You even see people with advanced cases that want to do the same thing. They’ve been told they have to take ADT for two years but still want to stop sooner.

I’ve never heard of a four year limit with any ADT drug. I’ve been on it for eight years, Six years on Lupron and two years on Orgovyx. Of course I have BRCA2, so that’s one of the reasons I have to do that.

If someone is only on Orgovyx They may become castrate resistant after four years. That happened to me on Lupron after 2 1/2 years, but I keep taking ADT because some of my cells are able to be helped by ADT.