← Return to First chemo - carboplatin/taxol - what to expect - side effects?

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Hi- I just began my chemo on 1/6/26, carboplatin and taxol every 3 weeks for 6 cycles, 18 weeks. I have been on Steeroids and have felt pretty well, probably overdoing it. Last night my legs, knees, calves all started aching pretty severely, hard to sleep. I’ve tried ice, Tylenol, Advil etc. From reading this it does sound like a typical reaction. Does anyone have any suggestions or experience with doing any sort of fast or diet to help with the side effects?
I know it’s important to eat and hydrate but if I could make changes to avoid this discomfort I’d be willing to.
Thanks for sharing your experiences and insights. It makes this experience less overwhelming when you realize you are not alone.

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Replies to "Hi- I just began my chemo on 1/6/26, carboplatin and taxol every 3 weeks for 6..."

@lizziegil Welcome to our Gynecological Cancers group. I'm tagging @denisestlouie who had journey through chemotherapy last year. She had - still has - a team of physicians and providers who have worked with her on treatment, diet, exercise and lifestyle changes. She may have some suggestions for you based on her experiences.

May I ask a little more about the cancer that you being treated for? Any information you might like to share is very helpful to us in supporting you.

@lizziegil My cancer was also serous, my treatment was Carboplatin, taxol, and keytruda. So I probably had more reactions than you will with Keytruda added into the mix.
Just a couple of recommendations for you:
Claritin at bedtime, start the night before the infusion and continue for 5 days to minimize leg aches. Tylenol helped too.
I did Valter Longo's Fasting Mimicking Diet (FMD)for cycles 4-6. Since side effects tend to increase as you go through your infusion schedule I cannot say if it reduced the side effects but I was less tired and nauseated.
The Diet, which is a 5 day modified fast, is supposed to put you into ketosis by the 5th day which weakens the cancer cells and causes the chemo drugs to be more effective. This diet has a lot of research behind it for cancer patients. I did not purchase the Prolon diet kit which was developed for the Fasting Mimicking Diet as I have too many food sensitivities but would have liked to just to keep things simple.
I had to create my own diet based on the nutrition information supplied for the FMD on the Prolon website. You eat around 800 calories per day so it is not a true fast and really is quite tolerable. The diet includes adding a bit of glycerin to your daily water intake to help you stay hydrated, it really works! Valter Longo uses the profits from the sale of the Prolon diet kit to fund further research, do a google search on Youtube, he is a rare, compassionate, humanity driven person.
You will loose a couple of pounds while on the FMD but will quickly gain it back when you return to your normal eating pattern.
Another thought is to make sure you walk every day, even when you are bone tired, walk around the block. Exercise is one of the main positive things you can do to keep cancer at bay. Movement also helps your blood circulation which is great for neuropathy.
Best wishes for smooth sailing as you proceed through your treatment schedule!

@lizziegil
My experience - Drink AT LEAST 64 oz water during Day 1 - 3 to flush out residual chemo. Ice chips or popsicles recommended during these days to avoid mouth sores.
I was exhausted Day 3 - 5 and with flu-like aches/pains. The good news is- I bounced back on Day 6 ! Don’t be discouraged in thinking the aches, pains, exhaustion will last because it doesn’t. You will come out of it.
My side effects got no worse in subsequent cycles.
Stay away from too much acidic foods. I found peanut butter crackers or anything peppermint was stomach smoothing.

@lizziegil I was diagnosed with serous papillary carcinoma May 2017- had a second opinion at Moffatt regarding treatment plan. Had same chemo as you and number. Then 3 Brachytherapy sessions for the vaginal cuff. The day after chemo treratment I was ok- days 2-3 terrible could not get out of bed but never nauseous just bad migraines. I hardly told anybody what I had- I wore gorgeous wigs (people wanted to know where I got my hair colored!) I looked great and I had no one living with me. I want to tell you the most important thing I did was to prevent neuropathy in the feet and hands is to ICE ICE ICE them while getting the chemo- have the staff bring tons of ice - you bring the plastic bowl and soak your feet the duration of receiving the chemo treatment. My hands I submerged in ice water- Ice packs would be ok as well. It is a pain to do but let me tell you I have NO signs of neuropathy maybe a tingle in my toes periodically whereas others have suffered greatly. I also had low level laser done to my feet once a week and got foot massages. This whole situation is truly mind over matter. I truly wish you the best. This too shall pass.