My original question was on behalf of my daughter. She is the one who had 3 internal melanoma tumors each 6 to 7 cm in size. They are all gone now, the one in the femur was destroyed by radiation. The tumor in her abdomen was removed surgically / this is how her melanoma was discovered. What her doctor thought was a benign cyst turned out to be a melanoma tumor. The immunotherapy was intended to target the tumor in her left lung and it worked. That tumor is now a carcass without metabolic activity. Unfortunately fluid collected in the pleura of her lungs when she went off of immunotherapy but steroids appear to have successfully stopped that bothersome problem.