@sma2 I'm so sorry to hear that you developed optic neuropathy in addition to the neuropathy in your feet! That's awful. Unfortunately the ethambutol is very toxic to a lot of people. My doctor never stressed all the possible side effects to look out for so I didn't realize early on that the weird feeling (neuropathy) in my feet might be caused by the drug until much later. My neurologist also told me there is nothing that can be done for neuropathy and I just have to wait to see if it gets better slowly. That's why I'm in a watch and wait mode right now. My MAC came back 3 months after I stopped the drug therapy after 16 months even though I was MAC free per my bronch results after 3 months on meds. Now twice a day I'm nebulizing 7% saline and I use an Afflo vest. I actually feel pretty good thankfully and can exercise on my treadmill quite vigorously without getting winded. I'm hoping I may be one of the lucky 25% according to some studies that are able to kick the MAC this way. We'll see.