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Carolyn, hi.
Lupus meds are much more complex: antimalarials, immunosuppressants (like methotrexate), anti-inflammatories, but more significantly the biologics targeting specific pathways.
Reclast reaction are best stopped initially because they aren't your body's response to the world, but your body's response to a specific trigger. I see two very different reactions. Long term responses can be promulgated by the cytokine reaction itself. Or they can be an allergic reaction that persists because a person is and remains allergic to something in the drug.
I'm not sure if I've answered. Ask me. I've no shortage of opinions.
Somewhere, I think in Korea, a university is trying a protocol of taking a steroid before the Reclast infusion. The steroid anti-inflammatories taken are quick short acting medications. These are the 5 day packs that are sometimes given for Reclast reactions.

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Replies to "Carolyn, hi. Lupus meds are much more complex: antimalarials, immunosuppressants (like methotrexate), anti-inflammatories, but more significantly..."

@gently
Geez, an allergic reaction never crossed my mind. Of course, that's a possibility.
Question? How long do you anticipate that an allergic reaction would last? Would you anticipate that it would wane a few weeks after the infusion but come back with a subsequent one?