@janwill Good Morning!
Welcome to the Epilepsy & Seizures group at Mayo Clinic Connect!
I did some quick research, and it looks like some patients do experience nausea when reducing Keppra. Interestingly, I had the opposite experience—I actually felt much more nauseous when my dosage was higher. I started at 500 mg twice a day, and my doctor gradually reduced it because of side effects. I feel so much better now with my lower dose.
As my doctor always says, every patient is unique!
How has your son been managing the nausea? Have you been able to check in with his doctor about what might help ease it?
Chris