Can chronic itching be caused by Neuropathy?

Posted by Rosebud @rosebud123, Feb 6, 2024

I have had Peripheral Neuropathy for about 20 years.
The only symptoms I’ve ever really had is a lot of tingling, numbness and spasms in the legs and toes.
For the past 12 months I’ve developed this chronic itch that started in my scalp but is now my whole body.
I have absolutely no rash or dryness anywhere.
My neurologist has told me he hasn’t heard of neuropathy causing itching which surprises me.
I’ve been to a Dermatologist who says he can’t see anything that’s causing it.
My Dr says she thinks it’s from high Uric acid.
In totally confused as to what it could be as it’s driving me crazy.
All three of them can only suggest Amiltriptyline which I’m not willing to take as I’m super sensitive to medication.
Has anyone here had the same problem and what did you do for it please.

Interested in more discussions like this? Go to the Neuropathy Support Group.

Benadryl worked on me and I used it for a while. I now take Alpha lipoic acid 600mg in the A.M. On an empty stomach.🦋

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Profile picture for armywac @armywac

You sound exactly like me. They keep saying that it is dry skin. But after multiple kinds of lotion, both off the shelf and prescription, nothing works. It seems to come and go on different parts of my body. I have found by recording it, that it always starts with a small lump under the skin. Who knows what is causing that, and then I break out all around it. After scratching until I bled, I did find something that seemed to help. Good old fashion Vaseline. it seems like it kills whatever causes the itch. Put it on your skin as soon as you start to itch. Good luck.

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@armywac I have PN from chemo. Mostly in my feet but a little in my finger tips. It exploded in my feet back in November that caused the oncologist to end my weekly chemo infusions 3 weeks early. I've lost 2 toe nails. Recently I developed an itchy rash on my feet that would not quit. My triage nurse prescribed triamcinolone 0.1% last week. The only thing that stopped the itching was a cool foot bath with Epsom salt and white vinegar. Nighttime was the worst. I saw my dermatologist yesterday who says the rash and itching is a sign of healing. Perhaps my nerves are starting to heal from the neuropathy. She too prescribed the triamcinolone but to cover it with Aquafor, wrap with plastic wrap 2x a day for about an hour. I did the plastic wrap one better and bought a box of disposable plastic foot covers. I choose to believe she's correct and the itching is a sign that I'm starting to heal from the chemo.

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Profile picture for botterd @botterd

@armywac I have PN from chemo. Mostly in my feet but a little in my finger tips. It exploded in my feet back in November that caused the oncologist to end my weekly chemo infusions 3 weeks early. I've lost 2 toe nails. Recently I developed an itchy rash on my feet that would not quit. My triage nurse prescribed triamcinolone 0.1% last week. The only thing that stopped the itching was a cool foot bath with Epsom salt and white vinegar. Nighttime was the worst. I saw my dermatologist yesterday who says the rash and itching is a sign of healing. Perhaps my nerves are starting to heal from the neuropathy. She too prescribed the triamcinolone but to cover it with Aquafor, wrap with plastic wrap 2x a day for about an hour. I did the plastic wrap one better and bought a box of disposable plastic foot covers. I choose to believe she's correct and the itching is a sign that I'm starting to heal from the chemo.

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@botterd ...That is great, but I am concerned about covering them up. Don't shut off the oxygen for very long to your feet. Be careful not to fall asleep with the plastic foot covers on unless they are very loose. Like you, I have used the Aquafor and it was useless, but I do hope that you have good luck with it. Different meds work different on each person. good luck to you

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Profile picture for armywac @armywac

@botterd ...That is great, but I am concerned about covering them up. Don't shut off the oxygen for very long to your feet. Be careful not to fall asleep with the plastic foot covers on unless they are very loose. Like you, I have used the Aquafor and it was useless, but I do hope that you have good luck with it. Different meds work different on each person. good luck to you

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@armywac thank you. The aquafor is to moisturize the dry skin. The real drug is the 0,1% triamcinolone. My dermatologist says to do this twice a day for no longer than an hour. I will not sleep in them. The triage nurse at the hospital last week also prescribed the triamcinolone but only to just rub it in. Fingers crossed.

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I have been experiencing spontaneous itching, persistent enough to draw blood in the past, for several years. It mostly occurs on my hands and on my calves/feet. After trying several preparations, I found that using the roll-on version of Cortizone 10 as soon as the itching begins has been very helpful. I also try to rub, not scratch, the area with a bath cloth to prevent bruising or bleeding. I wish you the best of luck!

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Profile picture for melindaheim @melindaheim

I have been experiencing spontaneous itching, persistent enough to draw blood in the past, for several years. It mostly occurs on my hands and on my calves/feet. After trying several preparations, I found that using the roll-on version of Cortizone 10 as soon as the itching begins has been very helpful. I also try to rub, not scratch, the area with a bath cloth to prevent bruising or bleeding. I wish you the best of luck!

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@melindaheim I might give the cortisone a try. It's worst at night and I can't stop scratching.

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Profile picture for botterd @botterd

@melindaheim I might give the cortisone a try. It's worst at night and I can't stop scratching.

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@botterd, good morning. If you do try the Cortizone 10, please let me know how it works for you. P.S. My computer struggles with the spelling of Cortizone, but that's what's on the container. 🙂

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I think the triamcinolone is stronger than otc cortisone and you're not supposed to mix them. I might try a little on my right hand that has some rash.

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Profile picture for botterd @botterd

I think the triamcinolone is stronger than otc cortisone and you're not supposed to mix them. I might try a little on my right hand that has some rash.

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@botterd

I was just prescribed this for issues in my left ear. Will see how it goes.

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I swear this works for me. If I start itching at night before going to bed. I grab my inexpensive bottle of CLEAR Calamine Lotion, Walmart Equate. Itching is gone within 10 minutes!

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