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Prostate Cancer Gleason 6 Group 1 + Hypogonadism

Posted by floridanad @floridanad, Jul 7, 2025

I recently was diagnosed with PC Gleason (3+3) 6 Group 1. I also have been on Testosterone Replacement Therapy for over 10 years. As soon as the biopsy result came back, I was told to immediately stop taking the Testosterone injections. This was 1.5 months ago. It has been recommended that I have the robotic DaVinci Prostatectomy so that I can resume the Testosterone Replacement Therapy the soonest. I am scheduled to see the surgeon who specializes in the DaVinci Prostatectomy next week. The effects of going off of the Testosterone have been oppressive, to say the least.

I know there are some studies that conclude that there is no connection between PC and using Testosterone, but has
anyone with Hypogonadism and a similar PC diagnoses been allowed to take Testosterone injections during or after this process?

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

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bobgolf | @bobgolf | Jan 5 11:24am
In reply to @floridanad "@bobgolf Between the time my original Urologist took me off of Testosterone until the Urologist at..." + (show)
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@bobgolf Between the time my original Urologist took me off of Testosterone until the Urologist at Moffit Cancer Centers put me back on, was at least four months. My T levels went down to 51! I couldn't swing a golf club or function normally. I was a mess. This cancer is very slow growing, so we have time. Like you, I will be proactive if and when there is an increase. Statistically, I may be more likely to die of old age before this cancer becomes a real issue. So I too have learned to just live with it.

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@floridanad your situation sounds similar. I went off the T for about 2 weeks to see what would happen and had my levels tested. I also went below 50. I mainly get fatigued easily, need a nap, no interests in sex at all, just a tired guy. So I am hopeful I can stay on the T as long as possible but understand the day may come when my prostate cancer dictates otherwise.

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