I completed 4 months of Orgovyx two years ago. I still had/have nasty side effects, including hot flashes, visceral fat, weakness and mild ED. I started TRT about 8 months ago, on advice of several Urologists and ROs. My T level rose from 250 to over 400, but, the side effects never stopped. I've been tapering off TGel and now only take 1 pump every other day since it doesn't cure my issues with this AWFUL drug that has seemingly rewired my hormonal system. My urologist also said that taking TGel will reduce my ability to produce it naturally. I've exhausted all the urologist paths having seen 3 from two different institutions. I have an appointment with endocrinology next to see if they can shed some light on the mystery. The Orgovyx side effects have been far worse than those from RT.