@stonewheel
You need to understand the "fight or flight response" that occurs naturally in response to stress. Prednisone is an artificial way to elicit this response because it replaces the naturally occurring hormone called cortisol.
PMR might be caused by stress as many people report. The pain might be an early warning signal. I have no doubt that I was under too much stress when my PMR symptoms started. In the beginning, the dots that I connected were looking like PMR with a capital "P"
After Prednisone was started more and more dots started to show up. I tried to connect all of the extra dots because I wanted answers. As more and more dots emerged and I connected those dots ... it became clear to me that the dots were spelling out Prednisone.
In essence ... Prednisone puts the body in a long term fight or flight mode.
https://www.verywellmind.com/what-is-the-fight-or-flight-response-2795194
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When I started thinking in terms of the fight or flight response and how the hormone cortisol works in the body everything started to make more sense to me.
The sequence of events leading up to my stay in the intensive care unit was a turning point for how I thought about Prednisone. When you carefully read the above link you will see --- "The body's blood clotting ability also increases to prevent excess blood loss in the event of injury."
I think prednisone is okay in the "short term" but not so good in the "long term." Every medical research paper I have ever read has said basically the same thing.
@dadcue makes perfect sense. The complexity of human (all multi-celled organisms) amazes me. Please define what you mean by “short term” and “long term” regarding Prednisone.