@zinnia55 did you start LDN at 3mg?? That's way too high a dose, too fast which no doubt is the reason you are having issues. You have to start with a very low dose! I've done a deep dive in LDN, I've been on it for 6+ years and I studied it for a year before I went on it. I wish doctors who prescribed it knew more! Here's the regiment.
0.5 mg at night, x3 or 4 weeks.
1mg at night x2 weeks
1.5 mg at night x2 weeks.
2mg at night x2 weeks.
Then can go to 2.5 or 3 depending on your tolerance.
If you are having insomnia or lucid dreaming, go back down on your dose for a while.
You said you hoped you could be on it long term. LDN should only be used long term as it can take a long time to help. You can not take opioids when on LDN! (It renders opioids useless and will not help pain.) If someone can't go off of opioids, you can't take LDN.
Many times people feel like it's not helping after they've been on for 6 months or a year and you don't realize till you go off of it that it actually was helping. I don't feel it helps my OLP at all as I always have lesions in my mouth but I guess it could be worse?
If you are taking LDN in the morning with nausea, it's always best to take it at night anyway. The lowest amount you take and it helps, the better - usually 2.5 to 3.5 for a while before going up higher if you must. It works by having a very short halflife.
Side effects mostly only happen if the dosage is too high, too fast. Don't give up.
I hate that people don't have a good experience just because doctors don't understand how it works and how to prescribe it.
And its not a magic cure. Its an anti inflammatory. But it can be used for many conditions including parkinsons, some cancers etc. Its only fairly newly recognized as helpful with many disorders but LDN is always an off label use of Naltrexone 50 mg which is used for drug addiction. There are also very specific ways it needs to be prepared by a pharmacy who knows the medication powder and what country it is coming from. If someone is finding no value, it may be a bad manfacturer in India, China, Israel.
It is mostly used for chronic pain but its anti-inflammatory properties are helping autoimmune issues sometimes, like OLP.
@bebold Hi! Thank you for the information. As of today I am on 1.5 mg(made at a local compund pharmacy) and I take in the am with food which seems to help with the side effects (ridiculous constipation). My Dr. was out of town for the holidays so I am waiting to hear back if he wants me to go down to 1 mg. I did like taking it at night but its just too hard on my stomach. I am sticking with it as long ass I can work out the kinks because I can see my mouuth is healing not just calmed down but actually healing and I really want to put this into remission. I wanted to try the troche but it turns out they make it with citric acid and thats a trigger for me. Do you have oral lichen planus? Are you in remission and still on LDN? Thanks you for the feed back!