Strontium citrate (Algaecal) and fractures
I am looking to see if there are any studies done that show a reduced chance of fracture from using Strontium citrate (Algaecal) as opposed to calcium. Everything I have read only mentions increase of density using it. Does anyone have doctor input or a study showing an decrease in bone fractures?
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@loplady I tried the Strontium Boost by Algae cal, but hat a bad reaction. I can't prove it was the strontium boost, but about 30 minutes after taking, I had heart palpitations. Lasted about 15 minutes, but certain it was the strontium as I took nothing else before bed.
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2 Reactions@loplady
Strontium RAnelate continues to be used in Europe.
All studies on strontium of any kind are studies on strontium; the additives are important when you consider side effects but strontium is the only bone builder in strontium ranelate or strontium citrate.
There is more research on strontium via ranelate because it has a multi million dollar pharma stake behind it; strontium citrate is just a supplement, but there is some research. I will do a quick copy and paste below so there may be duplicates here, plus I will not try to copy and paste all the uses in dental and surgical implants.
Strontium citate studies:
Mots/ComB overview:
https://strontiumforbones.blogspot.com/2017/02/mots-and-comb-study-comparison.html
Algaecal study:
https://pubmed.ncbi.nlm.nih.gov/21492428/
Mirza study:
https://strontiumforbones.blogspot.com/2018/02/bmd-increases-by-varying-amounts-with.html
Moise study:
https://strontiumforbones.blogspot.com/2014/10/monitoring-bone-strontium-intake-in.html
Another:
https://pdfs.semanticscholar.org/bdce/ac5e3fae890f6dd1902cb45734b96433b165.pdf
One on rabbits:
https://onlinelibrary.wiley.com/doi/abs/10.1002/lary.26623
https://pubmed.ncbi.nlm.nih.gov/28485552/
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3 Reactions@blueberre
Many times the side effects for a supplement might be traced to the additives. You might try the AOR brand; they have the fewest additives in the strontium brands with which I am acquainted.
It is rare but not unheard of for strontium to cause side effects. We know this because most of the world's ground water and seafood contains strontium, some at very high levels. Still, the therapeutic dose can make a difference even though some areas of the world have higher levels than this in their ground water.
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1 Reaction@kathleen1314 Thank you!!
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1 Reaction@kathleen1314 Serious question, why are people like Keith McCormick, Dr. John Neustadt, Dr. Doug Lucas against Strontium? Two have their own supplements but they could add Strontium to their offerings. Dr. Neustadt said in a recent podcast with Doug Lucas that he doesn't like it because it skews a Dexa and he wants an accurate Dexa. That's it?
Well, a lot of these old concerns do stem from the dexa skews for strontium. Skews of about 10% greater for strontium users depending on the machine, because of their denser bones and how the radiation penetrates strontium differently than a more largely calcium bone.
Plus, doctors are bound by FDA authorizations and frankly led by their pharma representatives. That is actually how I was introduced to strontium; my endocrinologist had heard about the strontium ranelate being sold by a large pharma co in Europe and mentioned it to me in an office visit. I researched and surprise there was strontium citrate. Still, there has been quite a bit of research about strontium over the years, and it seems to have been ignored by the medical community.
But dexa.....
Those old dexa skew concerns are now very dated and don't "hold water" because of the TBS and the REMs. Both TBS and REMS are not affected in the same way by the denser aspect of strontium. Because of the use of TBS and REMS, more and more strontium users are showing tests that show good bone density and good bone quality.
So I would ask those doctors if they still have the same concerns. I would expect at least a moderation based on the consistent results for REMS and TBS and strontium users, but it is difficult for anyone to say "I was wrong", especially a doctor that may have mislead many patients. I do know several medical providers on Inspire are starting to moderate their antistrontium screes, but no apologies have been issued.
With good bone density, good bone quality and bone biopsies showing good density and bone quality and research showing significant lessening of fracture risk and few side effects, it is now very very hard to be "against" strontium.
Indeed, as I have said in the past, my endocrinologist told me to change nothing, and I have never known a doctor to tell a strontium user, with good results, to stop using strontium. It would be a strange doctor who would tell a patient with good results and who is not fracturing with no side effects to stop strontium and take another pharma drug.
Contact some of them and ask, I would be interested. They will probably give you the standard reply that "it is early days, and they will be interested to see more research and studies".
Ok, I asked AI google and copied your exact question. This was its answer:
"Experts like Keith McCormick and Dr. John Neustadt are cautious about strontium due to concerns over inaccurate DEXA scan results, the lack of large-scale clinical trials for the supplement form, and potential cardiovascular risks associated with the prescription form. Dr. Doug Lucas's position is less clear, with some sources suggesting he is an advocate for the supplement form as part of a specific protocol."
So the dexa concern is shot down by rems and tbs results, and if you will read my previous reply about the cardio risks that cropped up in one flawed population study then you can put that concern into context. Plus, there are several osteoporosis drugs that have written cardio concerns in their literature, (Evenity, Forteo, Prolia), so I don't understand the demands for strontium citrate to prove no cardio concerns especially when it has never had a cardio concern listed in any of its studies. sigh
I would like more large scale clinical trials on strontium citrate also. Indeed, I, like many doctors, never think that we have enough research. ha
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5 Reactions@kathleen1314
I may have missed this. Which strontium do you take?
All strontium is the same strontium in terms of bone building ability.
What differs are the additives and the monitoring bodies. I have used AOr monitored by the Canadian government, similar to a drug and containing few additives; I have used vitacost brand which is at a good price point.
I try to use a product that is just strontium citrate with few additives.
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1 Reaction@loplady Would the problem of Strontium causing inaccurate DEXA results be eliminated if patient discontinued taking Strontium 24 hours, possibly longer, before their DEXA scan---like taking calcium or iron needs to be discontinued 24 hours before a DEXA?
@loplady different Dexa machines give different results