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Treatment Dogma - Aggressive is not the same as intelligent
Prostate Cancer | Last Active: Jan 4 10:16pm | Replies (28)Comment receiving replies
@denis76 per Google there are some rare cancers that are known to produce mass quantities of testosterone, but I don't see anything to say there is anything more general than that.
I did find this:
https://corporate.dukehealth.org/news/study-solves-testosterones-paradoxical-effects-prostate-cancer.
... which if I read it correctly, suggests that the problems may be caused in the first place by low testosterone, making it sound like ADT is exactly the wrong thing to do. Is this possible? Is it likely? Is it true in selected cases? I guess research continues.
Replies to "@denis76 per Google there are some rare cancers that are known to produce mass quantities of..."
I'm shocked and completely baffled. Thank you for the article. Is there a scientific basis for it, not just general statements?
All our doctors unanimously say that survival prognosis depends on testosterone. The lower your testosterone levels, the longer you'll live; the higher your testosterone levels, the shorter your life expectancy. This is all included in all standards and all clinical guidelines, and everyone is treated the same (reducing testosterone levels as much as possible).
The article says the opposite: that in advanced stages, we should aim not to lower, but rather to increase testosterone levels! By the way, my doctor mentioned cases where PSA levels still rise even with low testosterone, but for most people, PSA doesn't rise even with low testosterone. What about statistics?
My PSA just dropped to 0, and resistance hasn't developed yet. I have Gleason 9, so the risk is high. I may not live to see a revision of this treatment paradigm for those in advanced stages, and I'll simply be sent to my grave. It turns out that sometimes you have to go all in and go against the doctors' wishes, but how can you go against what's written in the consultation documents? Going by trial and error? It's very risky!
I used to think about taking three Erleada tablets instead of four and getting ADT injections every three months instead of every month, but the doctors said that would open the floodgates for cancer and kill me.
I'm certainly not a doctor, but I think the transition to a phase of cancer resistance will kill me, and the possible solution to their situation is "like a seesaw, avoid cancer resistance at all costs."
One scenario is when billions of cells are sensitive to ADT, and the second scenario is when billions of cells are insensitive to ADT. Maybe this is the key principle of survival strategy. Sometimes I think that the manufacturers of expensive drugs favor the second option because they are essentially on the side of We're making a profit, and if we reverse the treatment strategy (which doesn't actually require expensive treatment, but just simple testosterone injections), it will impact the pharmaceutical industry's stakeholders.
I want to live. But I don't want the fight for life to be like a lottery just because someone wants to make money! Maybe I'm wrong.
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@carbcounter interesting-thanks!