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Profile picture for laura1970 @laura1970

If you were sick and needed stress dose steroids in the hospital the typical treatment is hydrocortisone 100 mg 3 times a day. If you are well and needed regular adrenal replacement typically hydrocortisone 15-30 mg 2 or three times a day. Prednisone equivalent 2-5 mg per day. Ask your doc about dividing the dose into 2 or three times a day, for example maybe 1 mg three times per day for the first few days.

But definitely do what your doctor recommends, my thoughts are just hypothetical.

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Replies to "If you were sick and needed stress dose steroids in the hospital the typical treatment is..."

@laura1970 Spacing out your prednisone does not mimic what your adrenal glands do naturally. Adrenal gland release based on the circadian pattern with the highest being between 6am and 8am. My understanding that spacing them out can actually encourage adrenal suppression, so it is definitely something that should be discussed with your doctor before doing it. I am sure there are some good reasons to split a dose, I am not a doctor so I don't know what they might be.