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DiscussionSmallest amount of prednisone for adrenal glands to work again?
Polymyalgia Rheumatica (PMR) | Last Active: 3 days ago | Replies (14)Comment receiving replies
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@laura1970 Spacing out your prednisone does not mimic what your adrenal glands do naturally. Adrenal gland release based on the circadian pattern with the highest being between 6am and 8am. My understanding that spacing them out can actually encourage adrenal suppression, so it is definitely something that should be discussed with your doctor before doing it. I am sure there are some good reasons to split a dose, I am not a doctor so I don't know what they might be.