@pesun, welcome. I added this discussion to the Brain Tumor support group as well.

I'm sorry to hear of your brother's disease progression. Genetic testing is used to learn more about the tumor in order to determine the most effective treatment. I can understand the feeling of urgency and wish to start with treatment sooner than later. However, with more information, the choice of treatment may have a higher chance of being effective.

Waiting is hard. I know your "family is concerned that waiting for genetic test results may delay potentially beneficial treatment." It may also be possible that starting treatment may result in your brother getting ineffective treatment and suffering unnecessary side effects.

These are all good questions to ask your brother's care team and the specialists in Heidelberg. Have you been able to schedule the second opinion appointment?