Last year I had my first Reclast infusion and had flu like symptoms for 2 weeks. Needless to say, I was nervous about getting my second infusion last week. It’s been three days and so far so good. I was told the initial infusion is much harder for our systems then follow up infusions because we will already have had the medication in our system from last year, so it won’t be as much as a jolt to the system.