@ccc1965

I had elevated ALT and AST enzymes within a month of taking anastrozole, and an MRI and CT scan showed a drug induced liver injury. I was then put on letrozole, and my enzymes have been in the normal range or only slightly elevated. Letrozole is not as hard on the liver as anastrozole. My oncologist said that aromatase inhibitors don't usually cause elevated liver enzymes, but I am hearing of more and more breast cancer patients talk about elevated liver enzymes. I wish you the best!