@csimadera1
I was on Lupron for six years and Orgovyx For three years. The drugs do the same thing and cause pretty much the same side effects.

Nubeqa is a good option. After six months, you may be able to stop Orgovyx since you are a 4+3.

You could do that and see if your PSA starts to rise again. If you were to stay on Nubeqa It probably would not rise for a long time, But it would make sense to stop both drugs and see how you’re doing.

The guidelines say that unless you have other aggressive issues, six months is enough ADT.

Were any of these things found in the biopsy intraductal, cribriform, Seminal vesicle invasion, EPE or ECE. (Extraprostatic extensions extra capsular extensions). They can make the cancer much more aggressive and extend the amount of time you need to be on ADT.