I was wondering if anyone in the group taking Xtandi has experienced shortness of breath as a side effect. I actually was initially on a clinical trial using daralutamide and about 2/3rds through the trial, I began having shortness of breath. Later that year, after the 12 month trial, I went on Xtandi and the shortness of breath has continued. Extensive testing of my heart and my lungs have ruled out either as the source. If I ask the question "what is different?" the answer is the medication. Just wondering if anyone else has had a similar experience. Thanks. PS...my psa is negligible at this point..