@mikejjb123 - happy new year. I have issues with GERD and occasional nausea but not colitis or auto immune other than thyroid issues so will address that portion of your question. I became more concerned about GERD with my lung issues so my ID Dr recommended a swallow test (coordinated by my gastroenterologist). They didnt find any aspiration but did recommend an upper GI so I will be doing that soon. I take Rx strength Pepsid but I don’t feel like it helps much. I have some concerns about switching to a PPi but it might be an option. Interestingly enough the speech pathologist did mention Reflux gourmet which I know others on this site have had good success with. I’m sure you know all the protocol about habits to help with GERD relief. I have the wedge pillow but keep sliding down so just got a small under knee pillow which helps. For nausea I keep Trader Joe’s ginger chews on hand and also have sea bands for acupressure and a relief band which is like a tens unit watch. Good luck with everything. Hope you can get some relief soon.