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My best advice is not to panic over your recent turn of events - you will be fine. Take your time assessing the various treatment options and talk to as many people as possible, then make the decision that's right for you considering your personal circumstances. I've discovered that almost everyone's situation, lifestyle, marital status, etc. are different, and that there's no single treatment option that's best for all, even though some people will try to convince you otherwise.

I was diagnosed at age 71 with a PSA of 5.65, Gleason score of 3+4, and a tumor confined to one quadrant of my prostate. There was a reasonable case for active surveillance, but ultimately I chose surgery because I wanted it gone, and was willing to live with the side effects. Thirty months later I've had a biochemical recurrence, and am now again trying to decide what to do.

I read a recent (2023) study in the New England Journal of Medicine that concluded mortality was essentially the same for men with non-aggressive prostate cancer, regardless of the treatment option they selected (https://www.nejm.org/doi/full/10.1056/NEJMoa2214122). I found this very reassuring, and I'm now seriously considering adopting an active surveillance strategy, and simply enjoying the rest of my life without further treatment.

I wish you the very best of luck in wading through all the information, and sorting out what you want to do. I found the process somewhat overwhelming, and the doctors not terribly helpful as they all seemed to have their own personal bias (urologist recommended surveillance, radiation oncologist radiation, and surgeon surgery). But, you will get through it and will choose what's right for you.

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Replies to "My best advice is not to panic over your recent turn of events - you will..."

@abinoone
Hi and thanks for posting that link which is very interesting. I also had RP relatively recently. Would hope to avoid futher treatment in addition if at all possible to ensure some q.o.l. Let me know what you decide. Good luck!

@abinoone If you read that study, it was for LOCALIZED PCa.
But is yours localized any longer? Where are the cells- lymph nodes, prostate bed, peritoneum, etc?
Sometimes the surgery itself ‘spills’ cancer cells into the body - the technique of wrapping the gland in plastic for removal is far from perfect.
So what may have been an isolated lesion within the gland originally is now extra- prostatic and more liable to metastasize.
Unless you know for sure (low Decipher, clear pathological biopsy with no cribriform or IDC) you really are taking a gamble.
I’m not trying to cause panic or alarm, but simply giving a different perspective. Best,
Phil

@abinoone I am right where you were at. I am 70 years old. 5 cores 3+4 and one 3+3, psa 5.7. Active surveillance, take it out, or radiation. I am still running everything thru my mind. Thinking about surveillance will go back in 6 months and check my psa.