@sueinmn Thanks a lot for your detailed explanation. I agree that a single CFTR genetic mutation may not cause CF, but it may be the contributing factor of Bronchiectasis or other atypical symptoms. In addition, many BE patients including me have family history of lung disease such as COPD, BE, TB, or lung cancer. I believe we all carry some genes that make us susceptible to lung disease. As I know that some genetic mutation affects protein synthesis.

Like you, I also have wheat intolerance, while I was not aware of it and took it all the time, which may cause a lot of inflammation in my body and this inflammation goes to lungs via blood circulation and cause BE. In Chinese herbal medicine, if your digestive system is not healthy, your lung will not be healthy. I agree with this as most of us are slim, hard to gain weight.

I don't cough at all so I use saline to help me. My doctor advised me that one vial is enough but I did not follow their advices. Walking is great but it is relatively mild and it is not strength exercise. I will follow your advice to adjust saline and exercise amount.