@colleenyoung I'm scheduled to start GemCap on Jan 8th. But, my DYPD test results now show I have an enzyme deficiency that causes serious risk (severe toxicity and/or death) if I am on Capecitabine. My oncologist wants to start at a reduced dose but I'm not sure I want to start it at all! Very disheartening...I'm considering Gemcitabine alone. I realize that the effectiveness will be limited if done that way, but quality of life is also important. No one has discussed mutations with me, not even sure if I was tested?? GemCap was chosen for the "lesser side effects", but now that has changed. I don't think I would tolerate Abraxane, a bit lost at the moment...