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My husband's PSA rose after two Lupron treatments. Thoughts?
Prostate Cancer | Last Active: Jan 3 1:36pm | Replies (17)Comment receiving replies
@northoftheborder
Hi North, they have me on Firmagon and Abiraterone. Will that slow the transition to castrate resistance?
Replies to "@northoftheborder Hi North, they have me on Firmagon and Abiraterone. Will that slow the transition to..."
@johndavis60 There are no guarantees, but hopefully it will. The LATITUDE trial show a significant improvement in overall survival for patients with high-burden (polymetastatic) castrate-sensitive PCa starting Abiraterone and Prednisone at the same time as ADT, and part of the huge, multi-track STAMPEDE trial showed that the benefit extends to patients with low-burden (oligometastatic) castrate-sensitive PCa as well.
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@johndavis60
It’s not Firmagon specifically that makes a difference. Any ADT to which they add an ARPI like Zytiga will delay the time it takes to become castrate resistant.