@caheil
It appears your husband has become castrate resistant Since he’s been on Lupron for one year.

Median survival after becoming castrate resistance is two years That means as many live longer as less. It’s been six years since I became cancer resistant.

I started Casodex for a little over a year right after it happened and then went onto Zytiga for 2 1/2 years and I’m now on Darolutamide (Nubeqa) For almost 3 years. The last 25 months I’ve been undetectable. Not bad for a two year median survival.

The drugs are great these days and your husband Should be on one of these drugs after Casodex starts to fail him. Just wanted to let you know the sequence of events that works for some people.