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← Return to First Pluvicto Infusion Soon: What can I expect?
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First Pluvicto Infusion Soon: What can I expect?
Prostate Cancer | Last Active: Feb 14 6:07am | Replies (35)Comment receiving replies
@lee1447
Hi, thank you for your post. My father has neutropenia as well and just recovered from a bad neutropenic fever. We are weighing on the possible side effects of neutropenia for Pluvicto as well. From what we have heard from many other patients, the side effects are stronger for people with bone Mets. Unfortunately, my father has lots of bone Mets. I want to ask you how your husband responds to Pluvicto? Did he experience worsening neutropenia? Did he require G-CSF for the treatment?
Replies to "@lee1447 Hi, thank you for your post. My father has neutropenia as well and just recovered..."
@mciao My husband developed febrile neutropenia after his first infusion of docetaxel; apparently it is quite common in that situation. However, my husband had several bone mets before he had all six Pluvicto infusions in 2024. He NEVER developed neutropenia or other effects on his white cell count from Pluvicto. Neutropenia was never mentioned to us as a possible side effect of Pluvicto by the radiation team or the urology team at Mayo Rochester either. My husband's main side effects from Pluvicto were decreased saliva, some extra fatigue, and issues with his appetite, all of which improved after he finished Pluvicto.
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My husband had no issues with neutropenia while on Pluvicto.
Unfortunately, even though he was in the top 1/3 of the people who responded positively to Pluvicto, his PSA has started to rise. He will be starting a clinical study in February that has shown positive results. I hope your father does well. Hang in there and stay hopeful!