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Has anyone experienced fatigue after taking losartan for years?
Heart & Blood Health | Last Active: Dec 30, 2025 | Replies (37)Comment receiving replies
I’ve been taking 25 mg of Losartan now for almost a year. For me it must be having a cumulative effect. It’s the only pill thank goodness I’m on; but the fatigue is overwhelming. I’m going to cut that little pill in half and see if the tiredness remains. I gave it a chance but cannot function feeling this overwhelming feeling of no energy…
Replies to "I’ve been taking 25 mg of Losartan now for almost a year. For me it must..."
@teddybear123
I've been on Irbesartan for about 10 years and though not what you're asking about it is a very similar drug and I've not had any problems with it save for easily bruising on my arms.
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@teddybear123 I never considered that Losartan 50 mg would give me fatigue, which is particularly chronic for me as I recover ever so slowly from standard arthroscopic surgery done in April '25 to my left knee. But my legs are chronically fatigued, and I feel it a lot after a slow 45 minute AM walk with my dogs. Thanks for the heads-up! I was leaning towards stopping my statin (Crestor) rosuvastatin due to this leg fatigue thing.