I have had very good luck with Low Dose Naltrexone. I take it in the morning and about 2-3 hours later, I get a burst of energy. I take 4.5 mg each morning after taking weeks to slowly titrate up from .5 mg. It initially gave me quite vivid dreams and after two weeks, gave me insomnia if I took it too late in the day ...so now I take it in the morning. I have had Long COVID since 2020 and I finally have the energy and breath to walk 2/3 of a mile every day...and it has taken most of my arthritis pain away. It does not stop the Long COVID fatigue completely as I crash about 1 pm but I can still get up most days at 430 pm and make dinner!

I hear some people are taking it in two small doses so they can plan on an energy spurt twice a day but have not tried that.