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Hydroxychloroquine v methotrexate

Autoimmune Diseases | Last Active: Jan 11 7:05pm | Replies (30)

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@cptrayes curious what dosage were you on?

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Replies to "@cptrayes curious what dosage were you on?"

@mah7925

I was overdosed by 25% with 400mg a day, but I spotted it at 6 weeks and reduced my dose to 300mg.

Both UK and US have the same advice, a safe dose for eyes is a maximum of 5mg per kg (2.25lbs) of bodyweight.

In the UK, they just bung people on 400mg even though the NHS advice in general and the specific advice from the Rheumatology department I was referred to is very easy to find and very clear.

And I was overdosed in spite of already having eye issues. I was furious about it.

Frankly it's a LOT more dangerous to eyes than they tell you. Perhaps 1 in 100 people will have changes on scan within a year. One in 13 will have irreversible retina damage on scan after 5 years.

And although that doesn't immediately noticeably affect vision, the damage can continue to get worse even though the drug has been stopped. And even if it doesn't do that it gives you a head start in the damage which will be caused by getting old and is resulting in older people having worse sight loss than they need have.