The first few weeks on Prednisone can be rough especially if your dose isn't high enough. You want to find a "stable" prednisone dose that works for you. Some doctors restrict your prescription so you aren't able to increase your dose without running out of prednisone. If you aren't getting enough pain relief within a week or two tell your doctor so your dose can be adjusted.

Going to bed feeling fine but waking up in pain is a common problem. I think this happens because your Prednisone dose doesn't last for 24 hours. Ask your doctor if you can take a small dose of prednisone in the evening to alleviate this problem.

Prednisone mimics the hormone in your body called cortisol. Your body won't appreciate rapid changes in your Prednisone dose. I think rapid increases in your prednisone dose are just as bad as rapid decreases. You will probably experience prednisone side effects when your dose is adjusted up or down.

In the early going it is more about getting your pain under control. At 10 mg you might need to increase your dose a tad to find your "lowest effective dose." You probably won't need to worry about decreasing your dose unless you have serious side effects from prednisone right from the start of treatment.

I think keeping a journal about how you feel and the changes that happen to your symptoms is a good idea,