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PSA doubling time calculator differences: What calculator do you use?
I just got my recent PSA results today. 12/22/2025 PSA 1.29 on 11/03/2025 PSA was 0.35.
I entered that information on the Sloan Kettering PSA doubling time calculator. The result was a doubling time of 0.9 months.
I entered the exact same information on he Omni PSA calculator and it said the doubling time was 0.56 months.
I am wondering why the were not the same? Is there a "best" calculator to use?
It really may not be relevant because they both indicate a very rapid doubling time. I have been on a treatment holiday for about 7 months. In that time my PSA has gone from 0.01 (04/25/2025) to 1.29. So my treatment holiday will be ending soon...
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@harry100
What type of treatment did you have? If you had radiation the PSA drops over time.
Do you have a large prostate and have been on antibiotics?
Do you have BPH?
All of these can cause the PSA to rise and/or fall.
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1 Reaction@jeffmarc
Hello Jeff,
I haven't been diagnosed yet. So I haven't started any treatment. I get my biopsy results on the 29th.
I have an enlarged prostate so I was prescribed a medication for it. Can't recall the name. It starts with a "T".
I apologize for not being more detailed.
@harry100
The drug you’re referring to is probably Tamsulosin, though there is a faint chance that it could be Tadalafil (Cialis) which can also be used to treat BPH.
You could’ve figured it out by doing this search
“what medicine starting with a T would be given for an enlarged prostate”
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1 Reaction@jeffmarc
Jeff,
You are correct. It is Tamsulosin.
0.56 sounds about right: PSA went up by a factor of almost 4X In just about 7 weeks - or almost 2 months…so it basically doubled in just over 2 weeks time…that’s pretty fast.
Don’t know why Sloan has you at 0.9 - all numbers entered correctly?
Phil
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1 Reaction@heavyphil
Yes. I entered the numbers and dates correctly. I think I did it at least three time and the results were all the same.
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1 ReactionGreetings:
I used copilot to compute the psa doubling time in days, and i agree that the numbers do give rise to alarm. You may want to get to a center of exelence asap.
4/25 → 11/3 0.01 → 0.35 192 ≈ 37 days
11/3 → 12/22 0.35 → 1.29 49 ≈ 26 days
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2 Reactions@denany
Tank you for the information. My PC care is at Northwestern in Chicago. They are considered a center of excellence.
@aldenrobert
Northwestern is a good place to go are you seeing
David J VanderWeele : Physician Profile: Robert H. Lurie Comprehensive Cancer Center of Northwestern University : Feinberg School of Medicine: Northwestern University
He is really highly recommended.
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1 Reaction@jeffmarc
Yes he is my main man at Northwestern. I really like him a lot. Very knowledgeable and is very centered on the patient and their needs. The other great thing about him and Northwestern is their team of oncologists. I have seen two radio-oncologists, a neurological-oncologist and will be seeing a cardio-oncologist in a few weeks. I am very happy with my care at Northwestern in Chicago
(even if it is a two hour commute each way). But Northwestern Medicine has many hospitals and doctors offices in the Chicago suburbs and exurbs. So I don't need to travel into the city for scans and lab work.
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