Yes, I have been on letrozole for 16 months. I started having foot pain a few months ago. It started out just in the morning, but now anytime I sit for 20 mins or more, when I get up the pain is bad. I walk like a duck because it hurts to let my feet bend until it eases up. I also now have heel pain. My wrist pain is also bad. I use ibuprofen and tramadol with minimal relief.