At age 91 I've had 3 of the prescribed 6 Pluvicto treatments. PSA dropped from 8.9 to 2.2 after the first two treatments. (PSA after the third treatment is not scheduled until next month) The most prominent side effect is a dry mouth which dissipates slowly after each treatment. Since the metastatic cancer was diagnosed and ADT started two years ago , fatigue and loss of strength has been issue, which I offset partially with exercise. Other than a biopsy I've had no direct no interventions to my prostate. As Coleen notes everyone is different. I'm still uncertain whether I'll benefit in the long run from Pluvicto, but I'll keep doing it as l can tolerate what have been fairly mild symptoms so far.